Dr. Guangyao Zeng


 

Dr. Zeng graduated from Xiangya School of Pharmacy, Central South University, and has served as the Director of the R&D Department at Geneham Pharmaceutical Co., Ltd. He specializes in the research and development of active ingredients from natural medicines. Dr. Zeng has presided over one provincial and ministerial-level project and has been a main researcher in two major national science and technology projects, one National Natural Science Foundation project, and four key projects at the provincial and municipal levels. He has applied for over 20 patents, with 4 granted, and has received the Hunan Science and Technology Invention Award. Additionally, he has published more than 20 papers in various academic journals.
Main scientific research achievements:
Since he started working, he has presided over one provincial and ministerial-level project (Research on the anti-tumor synergistic effect mechanism of Vitedoin A on Akt/mTOR inhibitor VBE-1, NO2009FG3142), participated in two major national science and technology projects as the main researcher (Preclinical study of modern Chinese medicine EVn50 against breast cancer based on PI3K/Akt/mTOR pathway, NO2009ZX09102-109, Development of mulberry leaf extract and its preparation, NO2009ZX09102-110), three provincial and municipal key science and technology projects; applied for 6 patents, of which 4 were authorized; won the Hunan Science and Technology Invention Award once; and published more than 20 papers.
Papers published in the past five years:
(1) Shuai Ning, Lei Zhang, Jinjin Ma, Lan Chen, Guangyao Zeng, Chao Yang, Yingjun Zhou, Xiaoli Guo and Xu Deng,Modular and scalable synthesis of nematode pheromone ascarosides: implications in eliciting plant defense response[J] Organic & Biomolecular Chemistry,2020,18(26):4956-4961
(2) Xu Deng, Yingjun Zhou, Yajing Wang, Jinjin Ma, Guangyao Zeng, Lingyang Yan, Jinbao Fan, Wei Cao, Divergent Reactivity in CuII-Catalyzed Oxidative Coupling between Indole/Tryptamine Derivatives and β-Arylacrylic Acids [J]: Organic Letters, 2019, 21 (23) : 9506-9511
(3) Xiaofeng Chen, Jinbao Fan, Guangyao Zeng, Jinjin Ma, Chenxi Wang, Yajing Wang, Yingjun Zhou, Xu Deng. Access to 3a-Benzoylmethyl Pyrrolidino[2,3-b]indolines via CuII-Catalyzed Radical Annulation/C3-Functionalization Sequence. The Journal of Organic Chemistry 2018, 83 (15) , 8322-8330
(4) Guangyao,Zeng,Zhaoquan,Wu,Wei,Cao,Yajing,Wang,Xu,Deng.Identification of anti-nociceptive constituents from the pollen of Typha angusti. Natural product research. 2020 .34(7):1041-1042
(5) Bao-Long Chen , Ya-Jing Wang, Hong Guo, Guang-Yao Zeng Design, synthesis, and biological evaluation of crenatoside analogues as novel influenza neuraminidase inhibitors. European Journal of Medicinal Chemistry 109 (2016) 199-205